Comparative evaluation of injectable Hyaluronic Acid (HA) versus injectable Platelet Rich Fibrin (I-PRF) as a pocket therapy along with scaling and root planing in patients with stage 2 periodontitis.
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- To evaluate clinical efficacy of Injectable Hyaluronic Acid and Injectable Platelet Rich Fibrin as an adjuct to scaling and root planing on clinical parameters in patients with stage 2 periodontitis.
研究概览
简要总结
AIM
To compare the results of clinical parameters between scaling and root planing alone group, injectable hyaluronic acid group and injetable platelet rich fibrin as an adjunct to scaling and root planing.
METHODOLOGY
This is a split mouth study design where 25 patients of both gender with stage 2 periodontitis(grade A) satisfying all the inclusion criteria will be enrolled for the study. For each patient 3 quadrants will be chosen and randomly allocated using computerized randomization method into three groups. Areas with deepest probing depths will be included for application of injectable hyaluronic acid and injectable platelet rich fibrin and is treated by scaling and root.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •Subjects diagnosed with stage 2 periodontitis (grade A) and willing for treatment.
- •Patients with periodontal pocket depth of less than or equal to 5mm in atleast 3 quadreants.
- •Minimum of 15 teeth should be remaining.
- •Patient of 25 to 55 years of age.
排除标准
- •Systemically compromised patients.
- •Use of antibiotics in the past 6 months Steroid or inflammatory drugs for 7 days in 3 months Known allergy to the above mentioned drugs/substance Smokers and alcoholic Pregnant and lactating women Periodontal therapy within 6 months Bleeding and clotting disorders.
结局指标
主要结局
To evaluate clinical efficacy of Injectable Hyaluronic Acid and Injectable Platelet Rich Fibrin as an adjuct to scaling and root planing on clinical parameters in patients with stage 2 periodontitis.
时间窗: All clinical parameters will be measured at baseline, 1 month and 3 months and Injectable Hyaluronic Acid and Injectable Platelet Rich Fibrin will be injected at baseline.
次要结局
- To compare the clinical efficacy of Injectable Hyaluronic Acid & Injectable Platelet Rich Fibrin as an ajunct to scaling root planing & scaling root planing alone on clinical parameters in patients with stage 2 periodontitis.(All clinical prameters will be measured at baseline, 1 month & 3 months & Injectable Hyaluronic Acid & Injectable Platelet Rich Fibrin will be injected at baseline.)
研究者
Dr Aparna Ashwarya
Coorg Institute of Dental Sciences