Total Laparoscopic Versus Open Aortic Surgery for Abdominal Aortic Disease. A Prospective Study With Propensity Analysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 228
- 主要终点
- Composite adverse events (bypass occlusion, bleeding, graft infection, redo)
研究概览
简要总结
This prospective study was designed to analyse the postoperative and long-term outcomes of total laparoscopic vs. open surgical repair of infra-renal abdominal aortic occlusive disease (AOD) and infra-renal aortic aneurysmal disease (AAA) in comparable groups of patients using a propensity analysis model.
详细描述
From January 2006 to January 2010, 228 consecutive patients who received an aortic bypass for AAA (n=139) or for AOD (n=89) were studied. Open repair was performed in145 patients (AAA=109, AOD=36) and total laparoscopic repair in 83 patients (AAA=30, AOD=53). One-to-one propensity score matching between study groups was done according to a difference in the logit of propensity score of less than 0.04 between each patient pairs in the study groups. Logistic regression with the help of backward selection was used to adjust the effect of treatment method for propensity score as well as other variables in evaluating postoperative and long-term outcome. A p value < .05 was considered statistically significant.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 30 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aortic occlusive disease (TASC C & D)
- •Aortic abdominal aneurysm with a diameter > 5 cm
排除标准
- •Patients with an occlusive disease amenable to stenting (TASC A & B)
- •Patients with an abdominal aortic aneurysm with an anatomy allowing the use of a stent graft (EVAR)
- •Patients with a life expectancy < 3 years or ASA 4 with a high operative risk
结局指标
主要结局
Composite adverse events (bypass occlusion, bleeding, graft infection, redo)
时间窗: 0 to 6 years postoperative
Any of these complications occurring during this time frame
次要结局
- Mortality(0 to 6 years postoperative)