The effect of intracuff air, 0.9% normal saline, 4% lignocaine or 1% propofol on intraoperative hemodynamics and its laryngotracheal morbidity after tracheal extubation. - ETTCP

Self Sponsored0 个研究点目标入组 120 人开始时间: 待定最近更新: 2023年6月26日

试验速览

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•Patients with ASA CLASS I/II.
•Age >=18 to 65 years maintaining a neutral position of the head and the neck
•No known laryngeal or tracheal defects
•Scheduled for elective Sx below neck under general anesthesia with endotracheal intubation
•Surgery duration of 60â??180 min
•BMI >30 Kg/m2
•Patients giving written & informed consent

•Patients with any neurological or psychiatric disorder,
•History of smoking, laryngotracheal diseases, Severe cardiovascular or respiratory disease,
•History of URTI within the last 10 days prior to the operation,
•Morbid obesity, allergies to anesthetic agents to be used, alcohol or drug addiction,
•Lung complications such as chronic obstructive pulmonary disease (COPD)
•Patients with a history of malignant hypothermia
•Surgery less than 60 min and longer than 180 min,
•Surgery in the Trendelenburg and Reverse Trendelenburg position,
•Nasogastric tube in situ, oropharyngeal airway introduced perioperative,
•Unsuccessful intubation in one attempt owing to unexpected complications with intubation,
•History of increased ICP, Intra Ocular Pressure, Ischemic Heart Disease.
•Patients with full stomach, history of gastric regurgitation, requiring rapid sequence induction, with anticipated difficult airway,
•Patients undergoing laparoscopic surgeries
•Cormack Lehane scores 3 and 4
•Absolute contraindication to the study drug.

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