Vascular Responses to High vs Low Repetition Resistance Exercise Training in Young Men
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Carotid-femoral pulse wave velocity
研究概览
简要总结
This study evaluates the effects of two types of resistance exercise training (higher-repetition, lower load vs lower-repetition, higher load vs control) on regional and local measures of arterial stiffness in trained young men.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Aged 18-30 years old
- •Non-obese (Body mass index less than 30 kg/m2)
- •Non-smoker
- •Healthy based on questionnaire responses
- •Resistance trained (Resistance training > 2 times per week for 2 years, minimum 1 lower body exercise session per week)
排除标准
- •Allergies to milk proteins (whey or casein)
- •Any acute or chronic illness, cardiac, pulmonary, liver, or kidney abnormalities, uncontrolled hypertension, insulin- or non-insulin dependent diabetes or other metabolic disorders-all ascertained through medical history screening questionnaires
- •Arthritic conditions
- •Individuals who consume any analgesic or anti-inflammatory drug(s), prescription or non- prescription, chronically will be excluded
- •A history of neuromuscular problems
- •Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications).
研究组 & 干预措施
Resistance exercise training
Whole-body resistance exercise training 4x/week for 12 weeks. Either 'lower-repetition, heavier-load' or 'higher-repetition, lighter-load' intervention.
干预措施: Lower-repetition, heavier-load (Behavioral)
Resistance exercise training
Whole-body resistance exercise training 4x/week for 12 weeks. Either 'lower-repetition, heavier-load' or 'higher-repetition, lighter-load' intervention.
干预措施: Higher-repetition, lighter-load (Behavioral)
Non-exercising control
Continue habitual physical activity for 12 weeks.
结局指标
主要结局
Carotid-femoral pulse wave velocity
时间窗: 12 weeks post exercise training
Assessed using applanation tonometry
次要结局
- Left ventricular mass(12 weeks post exercise training)
- Common carotid artery distensibility(12 weeks post exercise training)
研究者
Stuart Phillips
Professor
McMaster University