PRagmatic Trial Of Messaging to Providers About Treatment of Heart Failure (PROMPT-HF) at Inova
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 5,000
- 试验地点
- 2
- 主要终点
- Increased use of GDMT in patients with Heart Failure with Reduced Ejection Fraction
研究概览
简要总结
A randomized, single-blind intervention trial to test the comparative effectiveness of an electronic health record best practice advisory system that informs clinicians of guideline-indicated and FDA-approved heart failure medications currently not prescribed to their patients with heart failure versus usual care (no alert and how things are done currently). The purpose of the alert is to stimulate appropriate medication prescription for patients with heart failure and a reduced ejection fraction. This will be done across outpatient Inova clinics and at the five Inova hospitals.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age>18 Years
- •Seen by a Cardiologist in an Inova clinic or Inova hospital setting
- •Left Ventricular Ejection Fraction ≤40%
排除标准
- •Opted out of EHR-based research
- •Hospice care
- •Already receiving maximally titrated doses of each of the four classes of evidence- based HFrEF medical therapy
- •Prior heart transplant
研究组 & 干预措施
Alert when provider is entering orders
干预措施: Best Practice Advisory using Electronic Health Record (Other)
No alert, usual care
结局指标
主要结局
Increased use of GDMT in patients with Heart Failure with Reduced Ejection Fraction
时间窗: 30 days after randomization
The primary outcome for the trial will be the proportion of patients with HFrEF who have an increase in the number of prescribed evidence-based therapies for HFrEF (beta-blockers, ACE-I/ARB/ARNI, MRA, SGLT2i) 30 days after randomization.
次要结局
- All-cause hospitalization and all-cause mortality at 30 days(30 days)
- All-cause hospitalization and all-cause mortality at 90 days(90 days)
- All-cause hospitalization and all-cause mortality at 180 days(180 days)
- All-cause hospitalization and all-cause mortality at 1 year(1 year)