jRCT2031250576招募中不适用
A GLOBAL PHASE 2/3 INTERVENTIONAL STUDY OF PF-08634404 IN COMBINATION WITH CHEMOTHERAPY IN PARTICIPANTS WITH EXTENSIVE STAGE SMALL CELL LUNG CANCER
未提供0 个研究点目标入组 550 人开始时间: 待定
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 550
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
入排标准
- 年龄范围
- 18age old over 至 No limit（—）
- 性别
- All
入选标准
- •Histologically or cytologically confirmed extensive-stage small cell lung cancer (ES-SCLC).
- •Participants have not received systemic therapy (chemotherapy, radiotherapy, chemoradiation) for ES-SCLC.
- •Treatment-free for at least 6 months since last chemo/radiotherapy, among those treated (with curative intent) with prior chemo/radiotherapy for limited-stage SCLC
- •Have at least one measurable lesion as the targeted lesion based on RECIST V1.
- •Eastern Cooperative Oncology Group performance status of 0 or
- •Adequate organ function
排除标准
- •known active CNS lesions, including brainstem, meningeal, or spinal cord metastases or compression
- •Leptomeningeal disease
- •Clinically significant risk of hemorrhage or fistula
- •history of another malignancy within 3 years
- •active autoimmune diseases requiring systemic treatment within the past 2 years
研究者
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