NCT01961024已完成不适用
Postprandial VLDL-TG Metabolism
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- VLDL-TG storage in adipose tissue
研究概览
简要总结
In thise study, we aim to determine the effect of meal fat on VLDL-TG kinetics in type 2 diabetic and healthy subjects matched for BMI in order to elucidate the potential pathophysiological differences in VLDL-TG FA channeling towards oxidation and storage in abdominal and leg subcutaneous adipose tissue. Specifically, we want to measure, by way of fat and muscle biopsies, the quantitative postprandial storage of VLDL-TG FA's in skeletal muscle and adipose tissue in relation to a series of tissue specific proteins and enzymes that might be involved in regulating skeletal muscle and adipose tissue FA storage.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 30 Years 至 70 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Written consent
排除标准
- •Known diseases
- •Alcohol abuse
- •Regular use of medicine
结局指标
主要结局
VLDL-TG storage in adipose tissue
时间窗: 3 hours
次要结局
- 18F-THA fractional storage(6 Hours)
研究者
Esben Søndergaard
Post Doc, MD, PhD
University of Aarhus
研究点 (1)
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