Field Evaluations of Innovative Tools for Vector-borne Disease Control in Conflict-affected Communities:A Cluster Randomised Trial
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 2,400
- 试验地点
- 1
- 主要终点
- epidemiological outcome: malaria incidence
研究概览
简要总结
The aim of this study is to determine the effectiveness of a new spatial repellent (called Mesh) at repelling multiple disease vectors and, reducing clinical malaria rates in temporary shelters and camp settings. The design of the study will be a two-armed cluster randomised trial.
By conducting the research in challenging camp settings in the north of Nigeria, the MENTOR Initiative aims to determine whether Mesh can be effective in harsh camp conditions where communities are living in conflict area temporary shelters.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
盲法说明
Neither the deliverers of the intervention nor the outcome assessors are blinded to the group allocations.
入排标准
- 年龄范围
- 6 Years 至 10 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Shelters with 1 or more children from 6-10 years old
- •Shelters with an adult/head of the household
排除标准
- •Shelters without children from 6-10 years old
研究组 & 干预措施
Control
- Information and Education Campaigns (IEC) campaigns will formally encourage breeding site management through; good practice household-level water storage (covering and cleaning of water storage containers) and waste management (removal of potential breeding sites in and around the home).
- Epidemiological surveillance: test and treat malaria cases in children 6 - 10 years of age
Mesh
- Information and Education Campaigns (IEC) campaigns will formally encourage breeding site management through; good practice household-level water storage (covering and cleaning of water storage containers) and waste management (removal of potential breeding sites in and around the home).
- Epidemiological surveillance: test and treat malaria cases in children 6 - 10 years of age
- Mesh product distributed to households
干预措施: Mesh - spatial repellent impregnated with transfluthrin (2500mg) (Combination Product)
Mesh
- Information and Education Campaigns (IEC) campaigns will formally encourage breeding site management through; good practice household-level water storage (covering and cleaning of water storage containers) and waste management (removal of potential breeding sites in and around the home).
- Epidemiological surveillance: test and treat malaria cases in children 6 - 10 years of age
- Mesh product distributed to households
干预措施: Information and Education Campaigns (IEC) (Behavioral)
Mesh
- Information and Education Campaigns (IEC) campaigns will formally encourage breeding site management through; good practice household-level water storage (covering and cleaning of water storage containers) and waste management (removal of potential breeding sites in and around the home).
- Epidemiological surveillance: test and treat malaria cases in children 6 - 10 years of age
- Mesh product distributed to households
干预措施: test and treat malaria cases (Diagnostic Test)
结局指标
主要结局
epidemiological outcome: malaria incidence
时间窗: 7 months
Malaria incidence will be estimated as the total number of malaria episodes per person over the course of the trial.
entomological outcome: vector density
时间窗: 7 months
the relative infestation rate of disease vectors (females of any of Anopheles malaria vectors, Aedes aegypti, or phlebotomine sand flies
次要结局
- feasibility, acceptance and uptake of Mesh(7 months)