Parkinson's Progression Markers Initiative Online Study (PPMI Online)
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 500,000
- 试验地点
- 2
- 主要终点
- Unified Parkinson's Disease Rating Scale Ib & II
研究概览
简要总结
Parkinson Progression Marker Initiative Online (PPMI Online) is an observational study collecting participant reported information from people with and without Parkinson's disease (PD), for the goal of better understanding risk and predictive factors for PD.
PPMI Online is part of the broader Parkinson Progression Marker Initiative aimed at identifying markers of disease progression for use in clinical trials of therapies to reduce progression of PD disability.
详细描述
PPMI is a broad program that is expanding the goals of the original PPMI study, and will include this PPMI Online protocol, as well the PPMI Clinical [NCT04477785], PPMI Remote, PPMI Digital protocols (with external regulatory oversight). All participants in PPMI may be asked to participate in one or all of these protocols and their enrollment in these studies may occur in varying order. PPMI participants may also be asked to participate in additional PPMI companion studies (as they are developed), which may only involve a subset of PPMI participants based on their cohort designation
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Parkinson Disease (PD) Participants:
- •Male or female age 18 years or older.
- •Has received a diagnosis of Parkinson's disease
- •Participants without PD:
- •Male or female age 18 years or older.
- •Has not received a diagnosis of Parkinson's disease
排除标准
- 未提供
结局指标
主要结局
Unified Parkinson's Disease Rating Scale Ib & II
时间窗: Baseline to 240 months
Evaluates self-reported motor and nonmotor Parkinson's disease symptoms
次要结局
未报告次要终点
研究者
Caroline M Tanner
Protocol Co- Principal Investigator
University of California, San Francisco