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临床试验/ACTRN12621000432819
ACTRN12621000432819招募中未知

Effects of glycogen availability on skeletal muscle molecular responses to exercise in healthy adults

Dr Nolan Hoffman0 个研究点目标入组 10 人开始时间: 2021年4月16日最近更新:
适应症

试验速览

阶段
未知
状态
招募中
发起方
入组人数
10

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Randomised controlled trial
主要目的
Prevention
盲法
Open (masking not used)

入排标准

年龄范围
18 Years 至 30 Years(—)
性别
Male

入选标准

  • Participants will be recruited if they meet the following criteria:
  • Aged 18-30 y
  • BMI: 18.5-27 kg/m2
  • Recreationally active (i.e. target V02 max approximately between 40-45 ml/kg)
  • No cardiopulmonary abnormalities
  • No injuries
  • Pass the ESSA pre-exercise screening tool and/or obtain GP clearance to exercise
  • Able to ride a stationary cycle ergometer at high intensity and successfully complete the entire duration of the glycogen depletion exercise protocol

排除标准

  • Known cardiovascular disease or diabetes mellitus
  • Known bleeding disorder (i.e. hemophilia A [factor VIII deficiency]
  • Hemophilia B [factor IX deficiency]
  • von Willebrand disease, or other rare factor deficiencies including I, II, V, VII, X, XI, XII and XIII)
  • Major or chronic illness that impairs mobility or eating/digestion
  • Taking prescription medications (i.e. beta-blockers, anti-arrhythmic drugs, statins, insulin sensitising drugs, or drugs that increase the risk of bleeding [i.e. anticoagulants, antiplatelets, novel oral anticoagulants [NOAs], nonsteroidal anti-inflammatory drugs [NSAIDs], selective norepinephrine reuptake inhibitors [SNRI], or selective serotonin reuptake inhibitors [SSRIs]
  • Unable or unwilling to have a muscle biopsy
  • Weight has changed more than 5 kg in past 3 months
  • Currently on a restrictive diet
  • Unable to attend the lab based on ACU's campus in Fitzroy (inner suburb of Melbourne), Victoria for the 5 study visits for completion of study protocol

研究者

发起方
Dr Nolan Hoffman

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