Automatic Detection of Dyspnea in Mechanically Ventilated, Critically Ill Patients
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Correlation between the pressure-time-product of inspiratory effort and the MV-RDOS score.
研究概览
简要总结
The investigators will conduct a prospective, observational, two-center ICU study of 60 subjects on mechanical ventilation with respiratory failure of any cause.
详细描述
Inclusion criteria:
- Adults of either sex (≥18 years)
- Non-c0mmunicative, endotracheally intubated in the past 24 hours.
- Expected to require ≥24 hours of mechanical ventilation.
Exclusion criteria:
- Continuous neuromuscular blockade.
- Ventilated on Airway Pressure Release Ventilation mode.
Ventilator measured airway pressure and flow signals will be streamed at 31.25 Hz into 131.1-s time windows (epochs) for up to 5 days. A recursive algorithm will compute individual breath's inspiratory effort (Pmus) and calculate the inspiratory effort time-pressure product (PmusPTP cmH₂O·s·min-¹).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Correlation between the pressure-time-product of inspiratory effort and the MV-RDOS score.
时间窗: One year
The degree of correlation between the pressure-time-product of inspiratory effort and the MV-RDOS score will be determined with Pearson's coefficient of determination (R2).
次要结局
- Ventilator free days.(One year)
研究者
Celica Irrazabal
Director, Intensive Care Unit and Co-Principal Investigator
Hospital de Clinicas José de San Martín