Atherosclerotic Plaque Characterization Using Multispectral, Multicontrast High Resolution Cardiovascular Magnetic Resonance Imaging
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Characterization of plaque that is found in the carotid walls of patients who have atherosclerosis
研究概览
简要总结
The purpose of this study is to utilize high-resolution CMR carotid imaging for the characterization of carotid wall volumes and plaque content in patients with clinical significant carotid atherosclerosis. Patients who are scheduled to undergo an imaging procedure will be recruited from the cath lab. Upon enrollment, blood samples conventional and genetic profiling will be collected. For patients undergoing a carotid endarterectomy, tissue from the carotid vessel will be collected during their procedure. Comparison of the MR images with tissue and/or blood samples will be made. Length of time in the study will be approximately 1 day. There will be no study-related patient follow-up.
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age range >17 years of age
- •Surgical carotid artery disease
- •Provide written informed consent and Authorization for Use/Disclosure of PHI
排除标准
- •History of carotid trauma
- •History of middle or large vessel vasculitis
- •Refusal to provide written informed consent and Authorization for
- •Use/Disclosure of PHI
结局指标
主要结局
Characterization of plaque that is found in the carotid walls of patients who have atherosclerosis
时间窗: 2 years post study initiation
次要结局
- To evaluate the effectiveness of MR imaging in identifying these plaque characteristics(2 Years Post Study Initiation)