NCT02013739已完成不适用
Description of Insulin Resistance and Explanatory Variables in Patients With Chronic Heart Failure
Hasselt University1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2011年5月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Glucose tolerance
研究概览
简要总结
The purpose of this study is to describe insulin resistance in a general chronic heart failure population, in combination with muscle strength, body composition and cardiac function.
It is assumed that insulin resistance is increased in CHF patient, and that this is related to decreased muscle strength and decreased lean tissue mass.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosis of chronic heart failure for at least 6 months,
- •clinically stable (not hospitalized) for more than 3 months prior to the onset of the study,
排除标准
- •glucose lowering medical therapy
结局指标
主要结局
Glucose tolerance
时间窗: day1
glucose and insulin concentration measurements in blood during oral glucose tolerance test
次要结局
- HbA1c, blood lipids, BNP(day 1)
- Muscle strength: maximal strength tested on a isokinetic dynamometer(Day 1)
- Body composition: dual energy x-ray absorptiometry(Day 1)
- cardiac function: echocardiography, retrospective from hospital files(retrospective)
- Health-related quality of life: MLHFQ and Eq5d(Day 1)
研究者
Bert Op't Eijnde
prof. dr.
Hasselt University
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Mechanisms of Insulin Resistance in Critical Illness: Role of Systemic Inflammation and GLP-1HypoglycaemiaNCT01347801Rigshospitalet, Denmark40
已完成
不适用
Impact of INsulin Sensitivity on Cardiovascular Risk Markers During 10-20 Years of FOllow upIschemic Heart DiseaseStrokeHypertensionDiabetes MellitusNCT01412554Oslo University Hospital103
已完成
不适用
Mechanisms of Insulin Resistance in HumansInflammationInsulin ResistanceNCT00330967US Department of Veterans Affairs25
已完成
不适用
Insulin Resistance : Heart FailureHeart FailureCongestive Heart FailureNCT00486967University of Dundee147
已完成
不适用
Biological variation of insulin resistance on polycystic ovarian syndrome and effect of treatmentPolycystic ovarian syndromeNutritional, Metabolic, EndocrinePolycystic Ovarian SyndromeISRCTN58369615Hull and East Yorkshire Hospitals NHS Trust (UK)40