JPRN-UMIN000016830已完成未知
A phase II study of S-1 therapy for advanced/recurrent esophageal cancer resistant/intolerable to 5-FU, Platinum compounds, and Taxane (OGSG1404) - A phase II study of S-1 therapy for advanced/recurrent esophageal cancer resistant/intolerable to 5-FU, Platinum compounds, and Taxane (OGSG1404)
Osaka Gastrointestinal Cancer Chemotherapy Study Group (OGSG)0 个研究点目标入组 17 人开始时间: 2015年3月17日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 17
研究概览
简要总结
The disease control rate(DCR) was 46.7%. The response rate was 13.3%. The median progression-free survival was 2.0 months. The median time to treatment failure was 1.9 months. The median overall survival was 8.4 months, and the 1-year overall survival rate was 30.5%.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1) with active double cancers excluding carcinoma in situ and/or prior cancer cured with shorter than 5 year interval period 2) with uncontrollable DM 3) with a history of cardiac infarction and/or anxiety angina pectoris within 6 months 4) with uncontrolled arrhythmia 5) under continuous steroids medication 6) with liver cirrhosis 7) with active infectious disease 8) with pericardial fluid, pleural fluid and/or ascites which needs drainage except controlled pleural fluid or ascites 9) have a history of Grade 2-4 hypersensitivity (CTCAE ver.4.0) 10) with grade 2-4 peripheral neuropathy by CTCAE v4.0 11) with blood transfusion within 2 weeks and/or continuous bleeding 12) with a figure of interstitial pneumonitis except radiation pneumonitis 13) with metastatic lesions in the central nerve 14) patient with psychological disorder who cannot participate in this study 15) women pregnant and/or nursing or men who like to have children in future 16) Any patients judged by the investigator to be unfit to participate in the study
研究者
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