Home-Based Exercise Tele-Rehabilitation in High-Risk Veterans: Impact of COVID-19 Exposure and Socioeconomic Factors
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Change in VO2peak
研究概览
简要总结
The Coronavirus Disease 2019 (COVID-19) pandemic has resulted in catastrophic infections and fatalities across the nation. Many older Veterans with comorbidities are especially vulnerable to complications and poor recovery. This award will investigate the effect of a novel, home-based, supervised, group exercise tele-rehabilitation in Veterans recovered from COVID-19 on cardiopulmonary and physical function.
详细描述
There is an urgent need to understand the lasting impact of COVID-19 on the cardiopulmonary system to improve physical function and prevent long-lasting disability. Pertinent knowledge gaps regarding the post-recovery physiology driving any impairments need to be addressed to improve the quality of life in Veterans with prior SARS-CoV-2 infection. Further, it is important to devise successful rehabilitation strategies that can be safely conducted in a Veteran's home. Hence, the investigators propose to utilize VA Video Connect to deliver a home based, supervised group exercise program to Veteran COVID-19 survivors. The objective of this exercise trial is to determine the influence of COVID-19 on cardiorespiratory fitness, pulmonary and physical function and to investigate the effect of a home-based exercise tele-rehabilitation on these outcomes. The study design includes rural and urban sites and investigators with a history of VA rehabilitation collaboration. Moreover, the investigators will explore healthcare disparities related to COVID-19 which are associated with functional decline and may affect sustainability of exercise rehabilitation strategies deployed, if necessary, under social distancing restrictions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •documented COVID-19 > 90 days ago
- •diagnosis of 2 of following conditions: hypertension, diabetes, cardiovascular disease, chronic kidney disease, chronic obstructive pulmonary disease OR 1 condition and BMI > 30 kg/m2
排除标准
- •myocardial infarction (within 3 months)
- •exertional or unstable angina (chest pain that limits activity)
- •severe congestive heart failure (EF < 20% in last year or NYHA Classification III or IV)
- •uncontrolled hypertension (SBP >180 &/or DBP > 110 mm Hg at screening)
- •screening EKG with ischemia, complex arrhythmia, or high-grade block (per Minnesota Code)
- •poorly controlled diabetes mellitus (FBS>200 mg/dl, RBS > 299 mg/dl, or HbA1C > 10)
- •treatment for cancer except skin cancer (within 3 months)
- •peripheral vascular disease with claudication
- •severe arthritis limiting ambulation
- •neurologic disease limiting ambulation (weakness requiring assist device; severe neuropathy)
- •end stage liver disease (decompensated liver disease)
- •End stage renal failure (dialysis)
- •severe pulmonary disease (home O2, admission for dyspnea or pneumonia within 1 month)
- •high fall risk (history of falls, bone fracture)
- •dementia (based on Evaluation to Consent)
- •signs or symptoms of any medical comorbidity that would preclude exercise testing or training
- •exercises on routine basis (structured aerobic exercise > 3 time per week)
研究组 & 干预措施
Tele-exercise
Exercise training 2x/week at home. Sessions include circuit exercises of aerobic and resistive training stations which are led remotely.
干预措施: Tele-exercise (Other)
结局指标
主要结局
Change in VO2peak
时间窗: Baseline and after 12 weeks tele-exercise
physical fitness, units are ml/kg/min
次要结局
- chair stands(Baseline and after 12 weeks tele-exercise)
- Change in 2-minute step test(Baseline and after 12 weeks tele-exercise)