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临床试验/NCT05694104
NCT05694104已完成不适用

China Nutrition Fundamental Data 2020

Peking Union Medical College Hospital1 个研究点 分布在 1 个国家目标入组 54,677 人开始时间: 2020年8月24日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
54,677
试验地点
1
主要终点
Number of participants diagnosed with malnutrition

研究概览

简要总结

Malnutrition caused by reduced food intake or assimilation and varying degrees of acute or chronic inflammation is a serious and underappreciated risk factor for adverse clinical outcomes. Despite the substantial health and economic burden, malnutrition remains to affect a considerable proportion of hospitalized patients worldwide. Nationally representative studies from the USA, Australia, and European countries have reported prevalence figures in the range of 8.9% to 80.4%. However, national data in some resource-poor countries, such as China, the largest developing country in the world, are scarce.

We did the China Nutrition Fundamental Data 2020 in a large, nationally representative sample of Chinese adult inpatients to 1) Explore the relationship between nutrition and health; 2) Understand the capacity of nutrition services in Chinese medical institutions.

This project adopted a multistage, stratified, cluster-sampling procedure based on administrative divisions in China. For each participant, a structured interview was done by trained nutritionists or clinicians. The following data were acquired: weight change within and beyond six months, food intake change within two weeks, nutrition therapy during this hospitalization, and laboratory tests. We also collected information on participants' sociodemographic characteristics and medical history. We took physical measurements, including height, weight, waist circumference, hip circumference, mid-arm circumference, calf circumference, handgrip strength, and blood pressure following standard protocols. Body composition was measured using bioimpedance analysis (BIA). In total, 54677 inpatients from 291 project hospitals completed information collection.

In addition, we collected information on the number of beds, the nutrition support team, the nutrition treatment plan and the construction of a full-time nutrition physician or nutrition nurse, the routine monitoring methods, interventions, and distribution of brochures for patients with malnutrition or nutritional risk in each project hospital and 37 other hospitals based on the principle of voluntary participation. A total of 328 hospitals completed information collection.

This project will establish standards for nutrition risk assessment, diagnosis, and treatment of inpatients in China, promote the construction of clinical nutrition departments, and improve the nutritional status of inpatients.

研究设计

研究类型
Observational
观察模型
Ecologic Or Community
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Aged 18 years or older
  • Admitted to hospital within 24-48 hours (not emergency) due to tumor or digestive system, respiratory system, cardiovascular system, endocrine system, nervous system, and urinary system disease.

排除标准

  • With mental illness or memory disorder who were unable to answer questions correctly
  • Critically ill patients
  • Lack behavioral ability

结局指标

主要结局

Number of participants diagnosed with malnutrition

时间窗: The 1 day of the survey

For the diagnosis of malnutrition, we adopted the Global Leadership Initiative on Malnutrition (GLIM) scheme based on three phenotypic criteria (non-volitional weight loss, low body mass index, and reduced muscle mass) and two etiologic criteria (reduced food intake or assimilation, and inflammation or disease burden). To diagnose malnutrition at least one phenotypic criterion and one etiologic criterion should be present in patients with nutritional risk.

Prevalence of nutritional risk

时间窗: The 1 day of the survey

Nutritional risk was defined as Nutritional Risk Screening 2002 (NRS2002) score≥3.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Wei Chen

Professor

Peking Union Medical College Hospital

研究点 (1)

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China Nutrition Fundamental Data 2020 | 临床试验