JPRN-UMIN000001026已完成未知
The effects of high molecular weight sodium hyaluronate on JKOM score and urine CTX-2 concentration -A randomized comparative clinical study with loxoprofen as a control drug- - OA Study
Research Group of Cartilage Metabolism0 个研究点目标入组 300 人开始时间: 2008年2月13日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 300
研究概览
简要总结
The early efficacy of IA-HA was not inferior to that of NSAIDs, and the safety of early-phase of IA-HA was superior to that of NSAIDs for patients with knee OA.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 50years-old 至 80years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •;Taken glucocorticoids (intra-articular injection, oral use, external use) within previous 4weeks ;Taken NSAIDs (oral, suppository, external) within previous 2weeks ;K-L grade of contralateral knee is 4 ;Secondary OA of the knee (eg. traumatic OA of the knee) ;Patellofemoral OA (K-L grade of more than 3) ;Moderate OA other than knee ;Rheumatoid arthritis ;Having history of total knee replacement or total hip replacement ;Having history of anaphylactoid reaction to sodium hyaluronan or loxoprofene ;Peptic ulcer ;Abnormal dysemia, abnormal hepatic function, abnormal kidney function, abnormal heart function ;Aspirin-induced asthma or its history ;.Inappropriate patients from the doctor's viewpoint
研究者
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