跳至主要内容
临床试验/NCT04952233
NCT04952233Unknown不适用

Application Value of Deep Learning in Diagnosis of Cervical Spondylosis

Peking University Third Hospital1 个研究点 分布在 1 个国家目标入组 2,000 人开始时间: 2021年1月30日最近更新:
适应症

试验速览

阶段
不适用
入组人数
2,000
试验地点
1
主要终点
Compare the consistency between AI and clinicians in identifying cervical CT features (cervical curvature, alignment, intervertebral space, disc herniation, ossification of the posterior longitudinal ligament, spinal stenosis)

研究概览

简要总结

Compared with the personal experience judgment of physicians, deep learning can identify something more quickly, efficiently, and accurately The identification and diagnosis of diseases save the energy of clinical and imaging doctors and achieve an individualized diagnosis of patients Diagnosis and evaluation are beneficial to the formulation of clinical surgical methods and the improvement of patients' prognoses.

This study uses deep learning technology, through the big data of cervical spondylosis cases learn, to explore the use of deep learning The feasibility of identifying and analyzing the characteristic imaging findings of cervical CT images that may be suggestive of a diagnosis It is attempted to reach the level of artificial intelligence-assisted diagnosis of cervical spondylosis.

详细描述

Cervical spondylosis is due to cervical discs and intervertebral joints and their secondary changes to the adjacent spinal cord, nerve roots, and vertebrae Artery and other tissue structure, causing the corresponding clinical symptoms. Cervical spondylosis is a common and frequent disease among middle-aged and elderly people. The incidence of cervical spondylosis is 10 percent in people over 30 years of age and is higher among those who work at a desk.

Two kinds of cervical spondylosis are common: cervical spondylotic radiculopathy and cervical spondylotic myelopathy. The principles of treatment differ greatly, and the prognosis after treatment is also different. Precise preoperative imaging and clinical diagnosis are helpful to accurately estimate the effect of surgery and the prognosis of patients.

Therefore, to achieve early accurate diagnosis is to improve the cervical spine Key to the curative effect of the disease. Generally referred to as deep learning is a kind of pattern analysis method, through the combination of simple and nonlinear module for multi-level "character learning" or "said learning" model of each module to each layer (original input) data into a higher dimension, more abstract representation, when there are enough of these transformations, The initial "low level" feature representation can be transformed into "high level" feature representation, and complex learning tasks such as classification can be completed.

For the classification task, the features that are important to the classification are amplified by increasing the number of layers, and the irrelevant features are ignored.

At present, the main research methods include Convolutional Neural Networks (CNN), self-coding Neural Networks based on multi-layer neurons, and deep confidence Networks. At present, CNN is mainly used in the field of medical image recognition.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • No surgical treatment was performed before the imaging scan. Imaging report and clinical diagnosis of cervical spondylosis with or without ossification of the posterior longitudinal ligament.
  • Patients who visited the orthopedics department and emergency department of our hospital without any surgical treatment before image scan and no obvious abnormalities were found in cervical imaging CT.

排除标准

  • Surgery before image data acquisition;
  • Cervical cancer, tuberculosis, and fracture;
  • The lack of image data, the image is not clear.

结局指标

主要结局

Compare the consistency between AI and clinicians in identifying cervical CT features (cervical curvature, alignment, intervertebral space, disc herniation, ossification of the posterior longitudinal ligament, spinal stenosis)

时间窗: 2019-2021

Compare the consistency between AI and clinicians in identifying cervical CT features (cervical curvature, alignment, intervertebral space, disc herniation, ossification of the posterior longitudinal ligament, spinal stenosis)

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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