Comparative Study of The Effect of Botanical Extract Mouthwashes of Tea Tree Oil/Aloe vera and Chlorhexidine on Prevention of Ventilator-Associated Pneumonia in Admitted Patients in Intensive Care Unites

Shahid Beheshti University of Medical Sciences0 个研究点目标入组 62 人开始时间: 待定最近更新: 2022年8月29日

试验速览

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•To have oral endotracheal tube
•Age between 16 to 65
•Being at least 72 hours ventilated
•Absence of pulmonary infection based on the modified pulmonary infection clinical score (score less than 5 at the time of study entry)
•Absence of history of allergy to herbal compounds of tea tree oil or aloe vera (based on the history obtained from the legal guardian or the patient's companion)
•Absence of specific oral lesions or infections
•Absence of sepsis, pulmonary thromboembolism, absence of history and signs of aspiration, absence of orthodontics, atelectasis, inflammatory gastrointestinal or bile ducts diseases and severe liver diseases according to the diagnosis of a specialist doctor (based on physical examination and history obtained from the legal guardian or with the patient).

•Traumatization during intubation
•Transferring patient from the ICU (for any reason) or death before completing the study
•Patient extubation for any reason
•Withdrawal or unwillingness of the legal guardian of the patient to continue the study
•Observing side effects caused by using mouthwash such as hives, itching and skin rashes
•Sudden changes in the patient's clinical condition or breathing pattern
•The presence of defects in the patient's immune system

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