Deprescribing: a Portrait and Out-comes of the Reduction of Polypharmacy in Portugal
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 380
- 主要终点
- Willingness to be deprescribed after the intervention with open-questions
研究概览
简要总结
This study protocol comprises three phases. The first two phases will be nationwide and aim to evaluate the prevalence and patterns of polypharmacy and assess the barriers and facilitators of deprescribing perceived by older adults, as well as their willingness to be deprescribed and to self-medicate. The third and last phase will be a non-pharmacological randomised clinical study to measure the impact of enablement of older adults in their willingness to be deprescribed and related quality of life.
详细描述
Study design
This is a three-phase study:
- Cross-sectional, analytical study of the prevalence and patterns of polypharmacy, namely sociodemographic and clinical profiles (age, genre, area of residence and years of study) and about medication (number of drugs and their active component), in older adults attending Primary Care in Portugal.
- Cross-sectional, triangulation study of older adults' perception of Barriers to and Facilitators of Deprescribing, Willingness to be Deprescribed and Willingness to Self-medicate.
- Non-pharmacological randomised clinical study of the impact of enablement of older adults in their willingness to be Deprescribed and related Quality of Life.
Phase I: prevalence of polypharmacy in older adults attending primary care in Portugal Design Cross-sectional, analytical study.
Setting: Primary Care Centres in Portugal will be randomly selected from the five main-land Portuguese Healthcare Administrative Regions and two Autonomous Regions (Madeira and Azores), in order to obtain a national geographical representative sample.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients attending to the primary care consultation in the selected health centres.
排除标准
- •Being acutely unwell in the last three weeks
- •Refuse to participate
研究组 & 干预措施
Elderly Enablement
The investigators will give enablement tools and talks with their GPs about how to issue the problem of polypharmacy.
干预措施: Elderly Enablement (Behavioral)
Control
This will be the control group.
结局指标
主要结局
Willingness to be deprescribed after the intervention with open-questions
时间窗: six months
Assess the enablement of older adults while being Deprescribed in the rise of Willingness to be Deprescribed with two open-questions (one to assess the facilitators and the other to assess the barriers) together with their perception of medication (Beliefs about Medicines Questionnaire).
次要结局
- Quality of life after the intervention with EQ-5D(six months)
研究者
Pedro Augusto Simões
Doctor
University of Beira Interior