Impact of Diabetes Mellitus on Retinal Microvasculature in Patients Without Clinical Retinopathy Using Optical Coherence Tomography Angiography
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- DCP thickness
研究概览
简要总结
the aim of this study is to assess the impact of duration of DM on OCTA parameters in diabetic patients without clinical Diabetic retinopathy.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Type of DM: Type
- •Fundus examination: no macular edema or other signs of clinical retinopathy
排除标准
- •Ocular history : any history of significant ocular injury or disease that could affect the retinal microvasculature such as retinal vascular occlusion, glaucoma, or vitreo-macular disease, as such conditions have also been noted to show sub-clinical OCTA changes [13, 14].
- •Fundus examination: macular edema or any other signs of clinical retinopathy
结局指标
主要结局
DCP thickness
时间窗: baseline
foveal, average parafoveal \& average perifoveal
Deep Vessel Density
时间窗: baseline
foveal, average parafoveal, average perifoveal
Superficial Vessel Density
时间窗: baseline
foveal, average parafoveal \& average perifoveal
SCP thickness
时间窗: baseline
foveal, average parafoveal \& average perifoveal
FAZ metrics
时间窗: baseline
FAZ area, FAZ perimeter \& FAZ flow density
Sectoral superficial vessel density
时间窗: baseline
superior parafoveal, inferior parafoveal, nasal parafoveal, temporal parafoveal, superior perifoveal, inferior perifoveal, nasal perifoveal \& temporal perifoveal
Sectoral deep vessel density
时间窗: baseline
superior parafoveal, inferior parafoveal, nasal parafoveal, temporal parafoveal, superior perifoveal, inferior perifoveal, nasal perifoveal \& temporal perifoveal
次要结局
未报告次要终点
研究者
Mohamed Abdou Saeed
principal investigator
Sohag University