ISRCTN36285333已完成不适用
To assess the safety and feasibility of administering Dexamphetamine after stroke and its effect on cerebral and cardiac haemodynamics
niversity of Nottingham (UK)0 个研究点目标入组 42 人开始时间: 2005年10月28日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 42
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Clinical stroke 3-30 days post ictus
- •2. Ischaemic stroke on computed tomography (CT)/magnetic resonance imaging (MRI)
- •3. Motor weakness (Motricity Index arm 0-99 inclusive)
- •4. Patients expected to stay in hospital for a further 8 days
排除标准
- •1. Pre-morbid Barthel Index <12/20
- •2. Dementia
- •3. No enteral access in prescence of dysphagia
- •4. Moderate-severe hypertension (systolic blood pressure [BP] >160 or diastolic BP >100)
- •5. Clinical ischaemic heart disease, previous or current angina, myocardial infarction
- •6. Hyperexcitability or agitated states
- •7. Current hyperthyroidism
- •8. History of alcohol or drug abuse
- •9. Glaucoma
- •10. Predisposition to tics or Tourette Syndrome
- •11. Epilepsy or recent convulsions
- •12. Liver dysfunction (aspartate aminotransferase [AST] 3 x normal)
- •13. Renal dysfunction (creatinine >130)
- •14. Pregnancy and breastfeeding
- •15. Recent monoamine oxidase inhibitor (MAOI) usage
- •16. Porphyria
研究者
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