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临床试验/ISRCTN36285333
ISRCTN36285333已完成不适用

To assess the safety and feasibility of administering Dexamphetamine after stroke and its effect on cerebral and cardiac haemodynamics

niversity of Nottingham (UK)0 个研究点目标入组 42 人开始时间: 2005年10月28日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
42

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • 1. Clinical stroke 3-30 days post ictus
  • 2. Ischaemic stroke on computed tomography (CT)/magnetic resonance imaging (MRI)
  • 3. Motor weakness (Motricity Index arm 0-99 inclusive)
  • 4. Patients expected to stay in hospital for a further 8 days

排除标准

  • 1. Pre-morbid Barthel Index <12/20
  • 2. Dementia
  • 3. No enteral access in prescence of dysphagia
  • 4. Moderate-severe hypertension (systolic blood pressure [BP] >160 or diastolic BP >100)
  • 5. Clinical ischaemic heart disease, previous or current angina, myocardial infarction
  • 6. Hyperexcitability or agitated states
  • 7. Current hyperthyroidism
  • 8. History of alcohol or drug abuse
  • 9. Glaucoma
  • 10. Predisposition to tics or Tourette Syndrome
  • 11. Epilepsy or recent convulsions
  • 12. Liver dysfunction (aspartate aminotransferase [AST] 3 x normal)
  • 13. Renal dysfunction (creatinine >130)
  • 14. Pregnancy and breastfeeding
  • 15. Recent monoamine oxidase inhibitor (MAOI) usage
  • 16. Porphyria

研究者

发起方
niversity of Nottingham (UK)

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