Serum-Ascites Albumin Gradient Analysis in Cancer Patients in Palliative Care
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Serum-Ascites Albumin Gradient Prevalence
研究概览
简要总结
Current recommendations do not recommend the concomitant administration of albumin after ascites puncture in patients with ascites neoplasia unlike cirrhotic ascites. The etiology of ascites in cancer patients is multifactorial, particularly by hepatic invasion that can lead to ascites loaded with albumin. Ascites punctures therefore lead to undernutrition, recurrent early ascites by decreasing the oncotic pressure by hypo albuminemia and a state of anasarca affecting the quality of life.
详细描述
According to the recommendations, each ascites fluid must be sent for biochemical and bacteriological analysis.
Demonstrate the high gradient proportion (percent only, no threshold of significance required). The literature has already validated the importance of supplementing albumen with cirrhotic ascites. Demonstrating that some cancer patients have high gradients, this will be enough to make the practitioner think to supplement.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient over 18 years of age followed for a solid cancer in a palliative metastatic situation who had a puncture of ascites.
排除标准
- •Minor patient
- •Known cirrhosis
结局指标
主要结局
Serum-Ascites Albumin Gradient Prevalence
时间窗: 3 months
Elevated Serum-Ascites Albumin Gradient Prevalence in Palliative Cancer Patients
次要结局
- Metastatic sites(3 months)