Normal Liver and Spleen Stiffness Values Using Shear Wave Elastography in Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 434
- 试验地点
- 1
- 主要终点
- Normal liver and spleen stiffness values
研究概览
简要总结
This observational study aims to determine normal liver and spleen stiffness values in healthy children using shear wave elastography (SWE). The study will include participants from the pediatric age group without known liver or spleen disease. SWE measurements will be performed non-invasively to establish reference values. The results may contribute to improving diagnostic accuracy in pediatric elastography applications.
详细描述
Shear wave elastography (SWE) is a non-invasive imaging method used to assess tissue stiffness. While reference values for SWE have been established in adults, data regarding normal liver and spleen stiffness in children are limited. This single-center, cross-sectional observational study aims to establish normative SWE values for the liver and spleen in the pediatric age group. Children with no known liver or spleen pathology will undergo standardized SWE measurement under controlled conditions. Age-specific and sex-specific reference ranges will be analyzed, which may contribute to enhancing the clinical utility of SWE in pediatric practice.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Month 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy children aged 0-18 years
- •No known liver or spleen pathology
- •Written informed consent obtained from parents or guardians
排除标准
- •Known liver disease (e.g., hepatitis, cirrhosis)
- •Known spleen disease (e.g., splenomegaly)
- •Any history of liver or spleen disease
- •Age outside the 0-18 years range
研究组 & 干预措施
Healthy Children
This group includes healthy pediatric participants with no known liver or spleen disease. Each participant will undergo non-invasive shear wave elastography (SWE) to assess liver and spleen stiffness for the purpose of establishing normal reference values.
结局指标
主要结局
Normal liver and spleen stiffness values
时间窗: Day 1
This study aims to establish reference values for liver and spleen stiffness in healthy children using shear wave elastography (SWE).
次要结局
未报告次要终点
研究者
Mehmet Akif AĞIR
Pediatric Gastroenterologist
Selcuk University