Evaluation of clinical parameters, oxidative stress markers, and quality of life in mandibular third molar surgeries under different preemptive analgesia protocols: randomized, factorial, clinical trial.

niversidade Federal do Ceará0 个研究点开始时间: 2019年9月4日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•Healthy individuals (American Society of Anesthesiologists - ASA I) of both genders; aged 18-35 years; who are required to remove the lower third molars; will be invited to participate in this study. In addition, the following inclusion criteria will also be adopted: (1) third unerupted mandibular molars; (2) third molars that present, in panoramic radiography, similar patterns of root formation, position and degree of impaction when comparing the right and left sides of each volunteer.

•Will be excluded volunteers who meet at least one of the following criteria: history of photosensitivity; smokers; pregnant or lactating; users of medications that interact with drugs used in this study; patients with orthodontic bands in mandibular second molars; confirmed history of NSAID allergy; signs of any pre-operative inflammatory or infectious condition; systemic diseases; neurological disorders. In addition, the volunteer who has used any NSAID within a period of up to 21 days prior to the surgical procedure will also be excluded from the study because of the possibility of residual residual anti-inflammatory effects, which may influence the outcomes of the present study.

发起方

niversidade Federal do Ceará