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临床试验/NCT04311996
NCT04311996已完成不适用

Does Social Buffering Continue to be Effective Over the Peripubertal Period When Friends Share the Stressor Experience?

University of Minnesota1 个研究点 分布在 1 个国家目标入组 269 人开始时间: 2021年10月25日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
269
试验地点
1
主要终点
Cortisol AUCi

研究概览

简要总结

The purpose of this experiment is to determine whether social buffering by friends of stress physiology remains effective later in puberty when friends share the load versus when they provide support but are not undergoing the stressor with the target child. There are four conditions: (1) Friend and Target both undergo the stressor, (2) Friend provides support but does not undergo the stressor, (3) Unfamiliar Peer and Target undergo the stressor, and (4) Alone (no partner).

详细描述

Adolescents experience social evaluation stress frequently. However, it is likely that often they are not alone, but with friends who are also going through the same experience. Thus, it is possible that under these conditions, social buffering by friends does not wane over the peripubertal period. Participants will be assigned to social conditions while engaging in an evaluative stressor task.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

入排标准

年龄范围
11 Years 至 14 Years(Child)
性别
All
接受健康志愿者
是

入选标准

  • •sufficient vision, hearing, and language skills to provide verbal and written assent
  • •ability to see and read stimuli presented on the computer screen
  • •ability to hear verbal instructions provided by the experimenter and judges

排除标准

  • •premature birth (less than 37 weeks)
  • •congenital and/or chromosomal disorders (e.g. cerebral palsy, FAS, mental retardation, Turner Syndrome, Down Syndrome, Fragile X)
  • •Autism Spectrum Disorders
  • •history of serious medical illness (e.g., cancer, organ transplant)
  • •serious psychiatric illness
  • •systemic glucocorticoids or beta-adrenergic medication use

研究组 & 干预措施

Experimental: Alone

Experimental

There are four conditions: (1) Friend and Target both undergo the stressor, (2) Friend provides support but does not undergo the stressor, (3) Unfamiliar Peer and Target undergo the stressor, and (4) Alone (no partner).

干预措施: alone (Other)

Experimental: Friend and Target Both

Experimental

There are four conditions: (1) Friend and Target both undergo the stressor, (2) Friend provides support but does not undergo the stressor, (3) Unfamiliar Peer and Target undergo the stressor, and (4) Alone (no partner).

干预措施: Friend and target (Other)

Experimental: Friend Provides Support

Experimental

There are four conditions: (1) Friend and Target both undergo the stressor, (2) Friend provides support but does not undergo the stressor, (3) Unfamiliar Peer and Target undergo the stressor, and (4) Alone (no partner).

干预措施: Friend support (Other)

Experimental: Unfamiliar Peer and Target

Experimental

There are four conditions: (1) Friend and Target both undergo the stressor, (2) Friend provides support but does not undergo the stressor, (3) Unfamiliar Peer and Target undergo the stressor, and (4) Alone (no partner).

干预措施: unfamiliar peer and target (Other)

结局指标

主要结局

Cortisol AUCi

时间窗: 2 hours

Cortisol response to the TSST, measured as Area Under the Curve, increase from baseline. 7 Samples were taken during the course of the assessment, at (1) arrival for training purposes; (2) after the calming video, 30 minutes after arrival; (3) after 5 minutes of speech preparation; (4) after 10+minutes of speech and math performance; (5) 15 minutes after sample 4; (6) 10 minutes after sample 5; (7) 10 minutes after sample 6. Area under the curve at intercept (AUCi) is calculated using samples 2-7 with sample 2 as the intercept.

sAA AUCi

时间窗: 2 hours

Salivary Alpha Amylase response to the TSST, measured as Area Under the Curve, increase from baseline. 7 Samples were taken during the course of the assessment, at (1) arrival for training purposes; (2) after the calming video, 30 minutes after arrival; (3) after 5 minutes of speech preparation; (4) after 10+minutes of speech and math performance; (5) 15 minutes after sample 4; (6) 10 minutes after sample 5; (7) 10 minutes after sample 6. Of those, samples (2, 4, 5) are assayed for salivary alpha amylase (sAA) in micrograms per milliliter. Area under the curve at intercept (AUCi) is calculated using samples 2, 4, 5 with sample 2 as the intercept.

次要结局

  • Self Report of Stress(2 hours)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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