2022-500618-24-00招募中4 期
Prostate medication, metabolism and gut microbiota, PROMED.
Turku University Central Hospital1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2022年8月10日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- change of gut microbiota signature after two months of prostate medication (5-ARI, LhRH-analog/antagonist)
研究概览
简要总结
The general aim is to understand the interaction of prostate medical therapies and gut microbiota. Main objective is to investigate how prostate medical therapies (5-ARI, ADT) affect gut microbiota composition.
入排标准
- 年龄范围
- 18 years 至 65+ years（18-64 Years, 65+ Years）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •histologically confirmed prostate cancer or benign prostate hyperplasia
- •provision of signed and dated informed consent form
- •ability and stated willingness to comply with all study procedures and availablity for the duration of the study
- •male aged >18 years
排除标准
- •inability to comply with study procedures or unwillingness to participate in the study
- •age < 18 years
结局指标
主要结局
change of gut microbiota signature after two months of prostate medication (5-ARI, LhRH-analog/antagonist)
change of gut microbiota signature after two months of prostate medication (5-ARI, LhRH-analog/antagonist)
次要结局
- PSA response LhRH-analog/antagonist after 2 and 6 months of therapy
- change of gut microbiota metabolism after two months of prostate medication (5-ARI, LhRH-analog/antagonist)
- PSA response to 5-ARI after 2 and 6 months of therapy
- prostate volume change to 5-ARI treatment after 2 and 6 months of therapy
研究者
Peter Boström
Scientific
Turku University Central Hospital
研究点 (1)
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