ADDED VALUE OF 18FDG-PET-CT IN THE DIAGNOSIS OF INVASIVE FUNGAL INFECTIONS IN NEUTROPENIC PATIENTS - Value of FDG-PET-CT in fungal infections in neutropenic patients

niversitair Medisch Centrum Groningen0 个研究点目标入组 12 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

暂无简介。

•Adult patients (age > 18 years) with a hematologic disease who probably or possibly have an IFI. That means:
•* Prolonged (or expected prolonged) neutropenia (leukocyte count < 1,0x109 or granulocyte count < 0,5x109, or leukocyte count < 1,5x109 or granulocyte count < 1,0x109 and decreasing due to chemotherapy), and
•* Axillary temperature * 38, 5°C, not reacting on treatment with wide-spectrum antibacterial drugs for 72 hours, and
•* A positive HR-CT scan, suspect for an IFI and
•o A positive galactomannan-test in serum or fluid acquired by BAL, or positive in both materials (N<=6)
•o A negative galactomannan-test GM in both serum and BAL fluid (N<=6)

•* Patients with age < 18 years
•* Female patients who are pregnant
•* Patients with claustrophobia or other reasons that make the scanning impossible, such as unable to lie still, need of oxygen, and so on.
•* Patients who are hemodynamically instable
•* (Pre)terminal patients for which the investigation is too burdensome
•* Patients who may clinically not be able to undergo the study
•* Patients without prolonged or expected prolonged immunocompromised condition (less than 14 days)
•* Patients without positive signs of IFI on HR-CT

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