NCT00873951已完成不适用
Influence of Protein Hydrolysis on Dietary Protein Digestibility and Metabolism in Healthy Subjects
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement2 个研究点 分布在 1 个国家目标入组 26 人开始时间: 2006年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 26
- 试验地点
- 2
- 主要终点
- Postprandial metabolic fate of dietary N
研究概览
简要总结
Hydrolysis of dietary protein may impact their gastrointestinal kinetics and further metabolism. The primary goal of this work was to measure the metabolic fate of intact or hydrolyzed protein using a protein of good nutritional quality, i.e., casein. A second aim of this study was to assess the true ileal digestibility of dietary protein using different methods including the hydrolyzed casein method and to measure its possible effect on endogenous intestinal N losses in humans.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy subjects
- •BMI between 18 and 25
排除标准
- •allergy to dairy proteins
- •positive serology to AgHbS, HCV or HIV
- •pregnancy
- •abusive drug or alcohol consumption.
结局指标
主要结局
Postprandial metabolic fate of dietary N
时间窗: 0h-1h-2h-3h-4h-5h-6h-7h-8h postprandial
次要结局
- Differences in ileal digestibility determination according to the method used(8h postprandial)
研究者
研究点 (2)
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