NCT00793559Unknown2 期
Terlipressin Administration in Septic Shock Refractory to Catecholamines Bolus vs. Continuous Drip-Phase II
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- CI, SVR,HR,BP, noradrenalin administration,renal function
研究概览
简要总结
terlipressin is given to refractory septic shock patients who do not respond to noradrenalin in Israel and Europe. It is given by bolus injection. we attempt to investigate weather it is better to give it by continuous drip and avoid abrupt changes in BP and heart function
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •septic shock patients receiving above 0.5 mcg/kg NA
排除标准
- •allergy to terlipressin, CHF, IHD, pregnancy
研究组 & 干预措施
terlipressin bolus
Active Comparator
1 mg of terlipressin received one time only
干预措施: terlipressin (Drug)
terlipressin drip
Experimental
干预措施: terlipressin (Drug)
结局指标
主要结局
CI, SVR,HR,BP, noradrenalin administration,renal function
时间窗: 6 mo
次要结局
未报告次要终点
研究者
研究点 (1)
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