IRCT20151227025726N19已完成2 期
Determination of Voriconazole Plasma Concentration by HPLC Technique and Evaluating Its Association with Clinical Outcome and Adverse Effects in Patients with Invasive Aspergillosis
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 24
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 no limit（—）
- 性别
- All
入选标准
- •Patients with the age of 18 years and older
- •Patients who were initiated on oral or intravenous voriconazole for proven, probable, or possible invasive aspergillosis
排除标准
- •History of allergy or severe reaction to azoles
- •Aspergilloma or allergic bronchopulmonary aspergillosis
- •Concomitant use of carbamazepine, efavirenz, rifampin, sirolimus or Ergot alkaloids
- •Chronic invasive aspergillosis with duration of symptoms for more than 4 weeks
- •Severe liver dysfunction (total bilirubin, , alanine transaminase (ALT), aspartate aminotransferase (AST), or alkaline phosphatase (ALP) more than 3 times the upper limit of normal)
- •Receiving combination of antifungal therapy
研究者
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