Fatty Liver and Ectopic Fat in Overweight and Obese Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 56
- 试验地点
- 1
- 主要终点
- Liver status will be will be determined by liver biopsy, non invasive liver assessment. Biological and medical imaging parameters will be use to characterize our patients.
研究概览
简要总结
The aim of the study is to find new clinico-biological and medical imaging parameters associated with non alcoholic steatohepatitis in overweight and obese patients.
详细描述
Non invasive assessment of liver fibrosis and liver inflammation and steatosis is clinically relevant in patients exposed to non alcoholic fatty liver diseases.
The aim of the study is to find new clinico-biological and medical imaging parameters associated with non alcoholic steatohepatitis in overweight and obese patients.
Fatty liver and ectopic fat accumulation will be particularly assessed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •BMI between 25 and 40
- •ALAT level superior to normal level even after 3 months of diet
- •alcohol consumption < 20 g/j for women and < 30 g/j for men
排除标准
- •HIV, hepatitis B virus, hepatitis C virus positive
- •known hemochromatosis
- •glycemia > 1.26 g/L or under anti-diabetic treatment
研究组 & 干预措施
1
obese or overweight patients with fatty liver or ectopic fat
干预措施: liver biopsy (Procedure)
结局指标
主要结局
Liver status will be will be determined by liver biopsy, non invasive liver assessment. Biological and medical imaging parameters will be use to characterize our patients.
时间窗: at inclusion and at year 1
次要结局
- Non invasive liver assessment, biological and medical imaging parameters will be use to characterize our patients.(at year 1)