Iodine Nutrition During Pregnancy and Related Neonatal Physical Development
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 250
- 试验地点
- 2
- 主要终点
- urinary iodine (UI) concentrations
研究概览
简要总结
Recent studies have found, in both developed and developing countries, there is still a considerable number of pregnant women in iodine deficiency status.Our overall aim is to monitor iodine status of pregnant women in China, and to examine the correlation between maternal urine iodine concentration (UIC) and newborn physical development level.
详细描述
Background: Recent studies have found, in both developed and developing countries, there is still a considerable number of pregnant women in iodine deficiency status. Our overall aim is to monitor iodine status of pregnant women in China, and to examine the correlation between maternal urine iodine concentration (UIC) and newborn physical development level.
Design: prospective cohort study
Methods: During August - December 2015,250 participants(28-32 weeks' gestation) were selected to participate in the study.The investigators collect the spot urine samples(n=750) once every two weeks.
Setting: Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine.
Participants: 150 normal pregnant women and 100 pregnant women with gestational diabetes (28-32 weeks' gestation) and their newborns were selected to participate the study.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 22 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •22-35 years,
- •28-32 weeks' gestation,
排除标准
- •a known history of thyroid disease in the non-pregnant state and previous.
结局指标
主要结局
urinary iodine (UI) concentrations
时间窗: up to three months
次要结局
- thyroid stimulating hormone level of newborns(up to three months)
- daily iodine intake of pregnant women(up to three months)
研究者
qingya tang
Chief Physician
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine