NCT00200694终止4 期
Anti-Proteinuric Response to ACEI, ARB and Diuretics Combination.
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 入组人数
- 18
- 试验地点
- 1
研究概览
简要总结
Determine the best strategy for proteinuria lowering in patients with proteinuria > 1 g/day receiving ACEI and ARB combination: either increase of ACEI and ARB dosage or increase of diuretic dosage.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •proteinuria > 1 g/day with ramipril 5 + valsartan 80 mg/day for 2 months
- •proteinuria changes < 50% on 3 separate dosages over 2 months.
- •Exclusion criteria:
- •age < 18 or > 80 years systolic BP < 110 or ≥ 140 mmHg, serum creatinine > 250 mmole/L
- •serum creatinine increase on ramipril + valsartan > 20%
- •intolerance to ACEI or ARB
排除标准
- 未提供
研究者
研究点 (1)
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