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临床试验/NCT06473220
NCT06473220已完成不适用

Evaluation of the Effectiveness of Narrative Nursing in Patients With Alzheimer's Disease

Nanjing Medical University1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2022年10月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
100
试验地点
1
主要终点
MMSE sore

研究概览

简要总结

To explore the effects of narrative nursing on mental state, life ability and emotion of patients with Alzheimer's disease (AD).

详细描述

There is no effective clinical treatment, mainly through taking Western drugs to control the Alzheimer's disease, but the treatment cycle is long, the cost of drugs is high, and the patient's family nee care, resulds long-termting in a huge economic and psychological burden on the patient and family recipients. Narrative nursing is an intervention mode of psychological nursing.In practice, narrative nursing can guide patients to actively organize experiences into various events with certain practical significance, attach importance to personal feelings and experiences, promote the psychological growth of patients and promote the generation of upward motivation.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Clinical diagnosis of Alzheimer's Disease.
  • Forgetting is the main cognitive impairment;.
  • The patient has basic language communication ability.
  • Patients were treated with the same regimen.

排除标准

  • Patients with other common neurological and mental disorders (depression, psychosis, vascular cognitive impairment).
  • Patients with heart, liver and other vital organ dysfunction.
  • Patients with severe cardiovascular disease.
  • Patients with severe physical disorders.

结局指标

主要结局

MMSE sore

时间窗: After 1, 2 and 4 weeks after hospitalization

The simple mental state Intelligence Scale (MMSE) was used to evaluate the mental state of the patients before and after the nursing intervention. The scale was mainly composed of 5 dimensions, namely orientation ability, recall ability, memory ability, attention and calculation ability, and language ability, and contained a total of 30 items. The total score was 0-30 points, the higher the score, the better the mental state of the patients.

HAMD score

时间窗: After 1, 2 and 4 weeks after hospitalization

The score consisted of 17 items, including self-awareness, work and interest, gastrointestinal symptoms, weight loss, hypochondriasis, sleep difficulty, etc. The total score \< 7 was considered normal, 7 to 17 divided into possible depression syndrome, \> 17-24 were classified as having depression, and\> 24 were classified as major depression.

ESCA score

时间窗: After 1, 2 and 4 weeks after hospitalization

The self-care ability measurement (ESCA) scale was used to evaluate the practical self-care ability of patients in the two groups before and after nursing intervention. The scale was mainly composed of four dimensions: self-concept, health knowledge mastery level, sense of responsibility, and self-care practical skills, and contained 43 items with a total score of 0-172. It shows that the actual ability of self-care is better.

HAMA score

时间窗: After 1, 2 and 4 weeks after hospitalization

The score includes two dimensions: spirituality and physicality, with a total of 14 items, including gastrointestinal and digestive symptoms, depressive mood, sensory system symptoms, behavioral manifestations when communicating with others, somatic anxiety, cognitive function, etc. The total score is \> 28, which is classified as severe anxiety, 21 to 28 grades are anxious, 14 to \< 21 is classified as anxiety, 7 to \< 14 scores may have anxiety, and \<7 is considered normal.

次要结局

未报告次要终点

研究者

发起方
Nanjing Medical University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Fang Honglian

Principal Investigator

Nanjing Medical University

研究点 (1)

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