Physiological studies of kisspeptin on reproductive hormone secretion in humans

Imperial College London0 个研究点目标入组 250 人开始时间: 2020年2月17日最近更新: 2024年3月11日

试验速览

2020 Results article in https://pubmed.ncbi.nlm.nih.gov/33196464/ results (added 17/11/2020)

•1. Age over 16 years
•2. Ability to give informed consent
•3. Adult participants will be recruited with no known problems with reproductive function (normal fertility)
•3. Adult participants will be recruited with previous problems with reproductive function (reduced fertility)
•4. Availability to attend hospital visits during weekdays for study visits.

•1. History of any medical, psychological or other condition, or use of any medications, including over-the-counter products, which, in the opinion of the investigators, would either interfere with the reproductive hormone levels or potentially cause harm to the volunteer
•2. Pregnancy or breastfeeding
•3. History of hypersensitivity to any of the components of the infusions
•4. Treatment with an investigational drug within the preceding 2 months
•5. Volunteers who have or intend to donate blood or blood products within three months before or following study completion
•6. Volunteers with poor venous access.
•7. A history of alcoholism or substance abuse within the preceding 5 years
•8. A history of major haematological, renal, thyroid or hepatic abnormalities or significant cardiovascular disease
•9. A history of cancer
•10. Volunteers with a medical or psychological condition that would impair their ability to participate reliably in the study or give informed consent

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