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临床试验/CTRI/2024/08/072255
CTRI/2024/08/072255尚未招募2/3 期

A Randomised Controlled Clinical Trial To Study The Effect Of Yashtimadhu in Asthibhagna With Special Reference To Closed Undisplaced Fracture

Dr Rahul Suresh Kokare1 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2024年8月15日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
70
试验地点
1
主要终点
Reduction in sign and symptoms of asthibhagna after ingestion of Yashtimadhu

研究概览

简要总结

An evolution of human life began thousands of decades ago. As humans got evolved they dealed with health issues and to overcome this Ayurveda too took birth with humans. Ayurveda has maintained its herbal, panchabhautika therapies from that era till today. A frame work of body is formed by Asthi dhatu and due to trauma asthi dhatu gains discontinuation which is well stated in its nirukti .

अस्थिविश्लेषोऽत्र भङ्गेऽभिप्रेतः।

मा. नि. मधुकोष टीका (४४/१)

There are main two types of bhagna namely sandhimukta and kandbhagna which are further classified into 6 and 12 types respectively . Fracture not only restricts the physical movements but also cuts the social, economical, psychological movements of the patient. If proper management of Asthibhagna in suitable period is not done then it may leads to the permanent disability. Similarly, minimise the immobilisation period and early recovery with proper healing is the aim of fracture management. The principal of management of fracture includes pain management, reduction, immobilization and rehabilitation. Sushruta has been described the same principle like Anchhana (Traction), Peedana (Counter traction), Sankshepana (Correction of deformity) and Bandhana (Immobilisation) for Bhagna. A fracture is a break in the continuity of a bone. Fractures come under orthopedics branch which deals with the deformities, discontinuation related to bone. Open reduction and internal fixation are the procedures which are carried out when fractures are open but even some close fractures to need internal fixation. In this study, closed un-displaced fractures are going to be considered with POP slab.In Ayurveda management of fracture is done with immobilizing fracture with kusha (splint) which was prepared with application of lepa of wound-healing medicines with internal medication prepared from medicines having sandhaneeya effect. Apart from this many herbo-organic drugs are prescribed for early healing of fracture. Yashtimadhu is simple, easily available, cost effective and potent. The scientific evaluation of such drugs along with their fundamental principles is essential for their universal acceptance.  Yashtimadhu  being described by CHARAK SAMHITA as a medication which is given internally to the patients having fractures. Rasa, guna, virya, vipak of Yashtimadhu acts on dosha dhatu so that it can help in healing of bone. Yashtimadhu being a drug which even has its Sandhaneey and anti-inflammatory properties.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • Patients will be selected Irrespective of caste, religion, gender and socio-economic status.
  • Patients with closed un-displaced (long bone) fractures will be Included.

排除标准

  • Patients other than closed un-dispaced fractures are excluded.
  • Patients with known case of Diabetes Mellitus, Hypertension will be excluded.
  • Patients with pathologiacal fracture like osteoporosis will excluded.
  • Fractures requiring open reduction and internal fixation.
  • Patients with previous non-union, metastatic tumor will be excluded.

结局指标

主要结局

Reduction in sign and symptoms of asthibhagna after ingestion of Yashtimadhu

时间窗: For 25 days

次要结局

  • Where The Trial Group Stands In Comparison With Control Group(18 Months)

研究者

发起方
Dr Rahul Suresh Kokare
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Rahul Suresh Kokare

SMBT Ayurved College and Hospital

研究点 (1)

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