The Relationship Between Deep Venous Thrombus Characteristics and Venous Dynamics With Subsequent Thrombus Resolution and Post-thrombotic Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 35
- 试验地点
- 1
- 主要终点
- Thrombus Resolution
研究概览
简要总结
The goal of this study is to examine in vivo thrombosis characteristics with ultrasound shear wave elastography (SWE) and determine the relationship with thrombus resolution and postthrombotic syndrome (PTS) in patients with acute proximal Deep Vein Thrombosis (DVT).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of acute, proximal (popliteal and above) DVT with or without Pulmonary Embolism within 72 hours
- •≥18 Years Old
- •Exclusion Criteria
- •prior episode of DVT
- •contraindication to standard therapeutic anticoagulation
排除标准
- 未提供
结局指标
主要结局
Thrombus Resolution
时间窗: 3 Months after diagnosis of DVT.
Ultrasound images of lower extremity DVTs comparing the initial diagnostic image of thrombus to a subsequent study performed after 3 months of anticoagulation.The lower extremity venous system is divided into 12 segments. Each vein segment will be analyzed on initial ultrasound and recorded 0 (no DVT), 1 (non-occlusive DVT), or 2 (occlusive DVT). The follow up ultrasound will be analyzed per vein segment and recorded as no residual thrombus, minimal chronic post-thrombotic changes, \> 50% resolution, \< 50% resolution, near occlusive DVT, no change, and progressive DVT.
次要结局
- Post-thrombotic syndrome(6 months after diagnosis of DVT)
- Vein Specific Quality of Life(6 months after diagnosis of DVT)
研究者
Damon E. Houghton
Principal Investigator
Mayo Clinic