Personalized Objects Can Improve the Diagnosis of EMCS From MCS
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 21
- 主要终点
- The frequency of behavioral response elicited by the stimuli suggested by CRS-R scale and the personalized stimuli they prefer
研究概览
简要总结
In this study，researchers will use personalized objects to assess patients' level of consciousness in chronic patients in minimally conscious state (MCS).
详细描述
The Coma Recovery Scale-Revised (CRS-R) is an important tool for the assessment of behaviors in DOC.Clinical practice has shown that self-referential stimuli, such as the patient's own name and face, are more effective to elicit the patient's response than that of non-self-referential stimuli.
The item "Functional Object Use" was assessed by using personalized objects (e.g., cigarette, paper) and non-personalized objects, which presented in a random order.The rest assessments were performed following the standard protocol of CRS-R. The differences between functional use of the two types of objects was analyzed by Chi-square test.
Researchers expected to see some of the patients in MCS are re-diagnosed as EMCS with the using of personalized objects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 15 Years 至 70 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients in minimally conscious state;
- •patients with stable condition;
- •each patient has athletic ability to some extent.
排除标准
- •premorbid neurology antecedent;
- •patients in coma or vegetative state;
- •patients < 1 months after the acute brain injury.
结局指标
主要结局
The frequency of behavioral response elicited by the stimuli suggested by CRS-R scale and the personalized stimuli they prefer
时间窗: one week
次要结局
未报告次要终点
研究者
Yuxiao Sun
Undergraduate student
Hangzhou Normal University