Evaluation of Biomarkers in Patients of Osteoarthritis treated with Terminalia chebula

izams Institute of Medical Sciences0 个研究点目标入组 100 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•Subjects of either gender aged between 40 and 70 years, suffering from joint discomfort for at least 6 months duration, taking only an OTC analgesic medication occasionally and meeting the American Rheumatism Association(ARA) functional class I to III and radiological evidence of osteoarthritis, patients who have grade II to IV of the Kellgren and Lawrence scale in the knee joint X-ray and who record baseline pain scores of at least 40 mm on the Visual Analogue Scale(VAS), monitored at baseline visit, subjects agreeing to discontinue any use of analgesics during the study.

•Patients with severe osteoarthritis (ARA functional class IV), Patients with radiological grading - Kellgren and Lawrence scale ranging from grade 0 to grade I, patients on alternative system of medicine, any psychiatric disorder or who have been using systemic/intra-articular steroids within 12 weeks and hyaluronic acid in the last 9 months, or potential candidates for imminent joint replacement, Patients with uncontrolled hypertension or diabetes, hepatic or renal impairment, pregnant or lactating females, or with a recent trauma of the involved knee.

发起方

izams Institute of Medical Sciences