Packing of Perianal Abscess Cavities (PPAC) Trial: A Randomised Multicentre Trial Comparing Packing With Non-packing of the Abscess Cavity

North Western Research Collaborative0 个研究点目标入组 300 人开始时间: 2012年12月3日最近更新: 2012年12月4日

适应症

试验速览

阶段: 不适用
发起方
入组人数: 300
主要终点: Time to wound healing in days, defined as complete epithelialisation of the abscess cavity.

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

The aim of this study is to compare the effect of packing and non-packing on the healing rate of perianal abscess cavities. Secondary objectives are to assess quality of life, cost effectiveness and rate of abscess recurrence and fistula-in-ano formation. If there is no difference in time to healing and non-packing is shown to be safe, acceptable to the patient and cost effective, this approach may become more widely accepted.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
盲法: None

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Clinical diagnosis of acute primary perianal abscess
•Have undergone surgical incision and drainage as an emergency

排除标准

•The abscess is the sequelae of concurrent disease or trauma
•Fourniers gangrene is suspected
•Unable to give informed consent

结局指标

主要结局

Time to wound healing in days, defined as complete epithelialisation of the abscess cavity.

时间窗: 1 day to 6 weeks

time to healing will be assessed in days

次要结局

Quality of life scores as determined by the Euro QoL EQ-5D-3L(10 to 14 days)

研究者

发起方

North Western Research Collaborative

申办方类型

Network

责任方

Sponsor

相似试验

已完成

不适用

Packing of Perianal Abscess CavitiesPerianal InfectionsPeri Rectal AbscessAnus AbscessAbscess AnorectalPerianal Abscess

NCT03315169Manchester University NHS Foundation Trust433

已完成

不适用

A Perianal Abscess Cavity Packing vs no Packing.Ischiorectal AbscessPerianal Abscess

NCT04832529Dow University of Health Sciences70

已完成

不适用

Perianal Abscess Packing Randomized ControlledTrial Pilot StudyPerianal Abscess

NCT01853267Imperial College London14

已完成

3 期

Postoperative treatment of perianal abscess cavities: comparing the use of internal wound packing to external dressingsSurgeryDigestive SystemOral and Gastrointestinal

ISRCTN93273484Central Manchester University Hospitals NHS Foundation Trust433

尚未招募

4 期

Bone healing in dental patients

CTRI/2024/03/064064Tejas Suryawanshi