Feasibility Study of a Systematic Approach for Deprescribing of Statins and Proton Pump Inhibitors in Nursing Home Residents
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 75
- 试验地点
- 2
- 主要终点
- Decrease in pill burden (the dose of statins and PPI's)
研究概览
简要总结
Deprescribing, the process of safely reducing or discontinuing unnecessary or harmful medication, has the potential to decrease polypharmacy and improve health outcomes. In this study a structured implicit algorithm, focusing on both extrinsic medication factors (eg change in disease) and intrinsic patient factors (eg. pill burden) will be used.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participant uses a statin and/or a proton pump inhibitor.
- •Participant signs informed consent.
- •Participant is a nursing home resident.
排除标准
- •Participant is there for short term nursing home admission (<3 months)
- •Participant is there for hospice admission.
结局指标
主要结局
Decrease in pill burden (the dose of statins and PPI's)
时间窗: 3 and 6 months after intervention.
On T0 (intervention) and on T1 + T2 (3 and 6 months after intervention), we will measure the dose of PPI's and statins on the medication list of every participant. These are provided by the pharmacist.
Decrease in pill burden (the number of statins and PPI's)
时间窗: 3 and 6 months after intervention.
On T0 (intervention) and on T1 + T2 (3 and 6 months after intervention), we will measure the number of PPI's and statins on the medication list of every participant. These are provided by the pharmacist.
次要结局
- Feasibility to use this algorithm.(3 and 6 months after intervention)
- All possible negative side effects of deprescribing (e.g. nausea, symptom recurrence)(From intervention to six months after intervention)