ISRCTN52811271已完成不适用

Different prescribed doses of high volume peritoneal dialysis and outcome of patients with acute kidney injury: a randomised controlled trial

São Paulo State University (Universidade Estadual Paulista [UNESP]) (Brazil)0 个研究点目标入组 120 人开始时间: 2010年5月20日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Adults with Acute Kidney Injury (AKI) according to Acute Kidney Injury Network (AKIN) criteria
•2. Clinical diagnosis of severe acute tubular necrosis (ATN) caused by a recent ischemic or nephrotoxic injury. Severe ATN was defined as a history of prolonged and profound hypotension, severe nephrotoxic drugs overdose, or excess endogenous nephrotoxic pigments (hemoglobinuria, myoglobinuria). Diagnosis was based on clinical history, results of physical examination, relevant blood tests, and urinalysis (microscopical examination of urinary sediment), a fractional excretion of sodium that exceeded 1% and the findings on renal ultrasonography.

•1. Under 18 years of age
•2. Functional azotemia
•3. Urinary tract obstruction
•4. Acute interstitial nephritis
•5. Rapidly progressive glomerulonephritis
•6. History of chronic renal insufficiency (serum creatinine 43mg per 100 ml)
•7. Renal transplantation
•8. Pregnancy
•9. Severe hypercatabolism according to Scherier criteria
•10. Absolute contraindication for PD were recent abdominal surgery (less than one month)
•11. Multiple abdominal surgeries (more than three)
•12. Patients submitted to less than one session of high volume PD (HVPD), defined as 24 h.

发起方

São Paulo State University (Universidade Estadual Paulista [UNESP]) (Brazil)