Antenatal Screening for Hemoglobinopathies in a Tertiary Care Centre - One Year Descriptive Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 196
- 试验地点
- 1
- 主要终点
- Screening of antenatal women lessthan 20 weeks POG for hemoglobinopathies for the prevalence of hemoglobinopathies in antenatal women attending tertiary care centre
研究概览
简要总结
Hemoglobinopathies are group of diseases characterised by abnormalities both qualitative and quantitative in the production of hemoglobin. The WHO estimates that overall at least 5.2% of the world population carry a significant variant of hemoglobinopathies. The most effective approach to reduce the burden of the society is to reduce the incidence by implementation of carrier screening programme. Detection of carrier status using complete hemogram and Hb Electrophoresis during pregnancy assess prevalence of hemoglobinopathies in pregnant women and provides prospective parents with the option of prenatal diagnosis for testing their fetus for hemoglobinopathies and also increase awareness among general population about prevention of birth of genetically abnormal child.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- Female
入选标准
- •All Antenatal women with period of gestation less than 20 weeks(calculated by reliable LMP/scan) attending OBGYN OPD.
排除标准
- •women who are already known cases of hemoglobinopathies and who are not willing to participate in this study.
结局指标
主要结局
Screening of antenatal women lessthan 20 weeks POG for hemoglobinopathies for the prevalence of hemoglobinopathies in antenatal women attending tertiary care centre
时间窗: 1 year
次要结局
- To screen Preganant women for hemoglobinopathies and increase awareness among general population and offering prenatal diagnosis to couples at risk of having abnormal child(1 year)