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临床试验/NCT07262294
NCT07262294招募中不适用

The Effect of Deep Breathing Added to Core Stability Exercises in the Treatment of Patients With Ankylosing Spondylitis: A Randomized Controlled Trial

Beni-Suef University1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2026年2月1日最近更新:
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
30
试验地点
1
主要终点
Respiratory function

研究概览

简要总结

Exercise may be considered the gold standard for the management of mechanical and functional symptoms associated with patients having AS and they are considered as a safe and effective treatment for improving strength, spinal mobility, and physical fitness in general. However, there were no definite types or doses recommended over others.

Additionally, poor posture is one of the consequences of AS due to pain, loss of flexibility, and muscular weakness which may also affect respiratory function. This faulty mechanical posture of the thoracic and cervical spine may affect the pulmonary function of these patients. Therefore, the purpose of the current study is to investigate the efficacy of deep breathing exercises added to core stability exercises in the treatment of patients suffering from AS.

详细描述

The management of AS typically involves a multidisciplinary approach which includes both medical and physical therapy approaches, concerning the medical treatment, NSAIDs are widely used for pain relief and inflammation control in AS patients and were recommended for the management of patients having AS. The efficacy of NSAIDs has been well-documented in research studies, Disease-modifying antirheumatic Drugs (DMARDs), including sulfasalazine and methotrexate, play a crucial role in suppressing inflammation and preventing joint damage in AS patients, or biologics, such as tumor necrosis factor (TNF) inhibitors (adalimumab, etanercept, infliximab), have transformed AS treatment by specifically targeting inflammatory pathways and significantly improving symptoms and function.

Respecting the physical therapy approach plays a crucial role aims to maintaining and improving mobility, reducing pain, enhancing overall function, correcting mal-positioning, and improving patients' psychological status in patients with ankylosing spondylitis. It usually includes a combination of exercises such as Range of Motion (ROM) exercises, strengthening exercises, Cardiovascular exercises, postural training, patient education, assistive devices, Adaptations, and monitoring. Different types of exercises have been studied for managing patients having AS, however, no specific type has been recommended over others. Additionally, up to our knowledge, there were no studies has addressed the respiratory function that may be affected with patients having AS either from postural abnormalities, lack of spinal flexibility, or generalized functional limitations. Therefore, the current study aims to evaluate if deep breathing exercises as a complementary intervention would be of some value when added to core stability exercises for patients suffering from AS.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Outcomes Assessor)

盲法说明

Double blind

入排标准

年龄范围
25 Years 至 45 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Receiving the same medical treatment
  • Age range between 20 and 45 years
  • Includes both male and female patients
  • Diagnosed with stable ankylosing spondylitis (AS) for at least 3 months
  • Not engaged in any other rehabilitation programs within the last 6 months

排除标准

  • Presence of other systemic or neurological disorders
  • Any change in medication within the last 6 months

研究组 & 干预措施

Deep Breathing exercise plus Core stability exercises

Experimental

Deep Breathing exercise is a type of exercise that engage the diaphragm to enhance the respiratory function, improve lung efficiency, and induce relaxation which improve the overall health condition.

干预措施: Exercises (Other)

Core Stability Exercises

Active Comparator

Core Stability exercises are group of exercises designed to strengthen abdominal, back, lower limbs, and pelvis muscles which enhance posture and provide stability and body control during daily activities

干预措施: Exercises (Other)

结局指标

主要结局

Respiratory function

时间窗: Patients will be examined after 4 to 6 weeks

Forced vital capacity (FVC) which measure lung volume, and it reflects the capacity of the lung. Forced expiratory volume in 1 second (FEV1) which measure lung velocity, and it evaluate the presence of airway obstruction. FEV1/FVC it the index that differentiate between obstructive and restrictive lung disease.

次要结局

  • Functional exercise capacity(Patients will be examined after 4 to 6 weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mariam Abdel Rahman

Lecturer of Orthopaedic Physical Therapy

Beni-Suef University

研究点 (1)

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