JPRN-UMIN000035389招募中未知
Effects of dual initial combination therapy with macitentan plus riociguat or macitentan plus selexipag on hemodynamics in patients with pulmonary arterial hypertension - SETOUCHI PH study
Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science0 个研究点目标入组 76 人开始时间: 2019年4月1日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 76
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1) Patients without PAH 2) Patients treated with PAH-specific drugs 3) Patients treated with incompatible drug combination 4) Patients with bleeding or risk of bleeding 5) Patients with pregnancy or suspected pregnancy or patients with breast-feeding 6) Patients with atrial fibrillation 7) Patients with moderate renal dysfunction (serum creatinine 1.5 mg/dl) 8) Patients with moderate liver dysfunction (serum AST or ALT 2-fold of standard value)9) Patients with hypotension (systolic blood pressure less than 90 mmHg) 10) Patients with low cardiac output (cardiac index less than 2.0 l/min/m2 11) Patients included other clinical study 12) Patients recognized as inappropriate by attending physician
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