NCT00911365已完成2 期
A Double-blind Placebo-controlled Randomized Clinical Trial of Autologous Mesenchymal Stem Cells in Patients With Multiple System Atrophy
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 27
- 试验地点
- 2
- 主要终点
- Scores on unified MSA rating scale
研究概览
简要总结
This study is based on positive results in open label trial of mesenchymal stem cells therapy in patients with Multiple System Atrophy (MSA).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- — 至 75 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •75 Years Old or Less
- •Multiple System Atrophy
- •Voluntary Participants
排除标准
- •Doubted dementia (MMSE < 24)
- •Severe febrile condition
- •Serum SGOT/SGPT three times above
- •Malignant mass
结局指标
主要结局
Scores on unified MSA rating scale
时间窗: one month
The statistical difference between scores before and after autologous mesenchymal stem cells treatment of unified MSA rating scale will be measured every month and every year using paired t-test.
次要结局
未报告次要终点
研究者
研究点 (2)
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