IRCT20220424054645N1尚未招募3 期
Evaluation the efficacy of Livergol(Sylimarin extract) on liver function of thalassemia major and intermedia patients: A triple-blinded, randomized, placebo-controlled trial
Bandare-abbas University of Medical Sciences0 个研究点目标入组 80 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 1 year 至 18 years（—）
- 性别
- All
入选标准
- •Confirmed thalassemia major and intermedia cases with CBC and HB electerophoresis
- •Patients without anaphylactoid reactions to any medication
- •Patients with ALT rising more than two times of upper normal limit
- •Consent to participate in trial
- •Iron overload(serum ferritin of1000-5000ng/l) during 6 months before study
- •Negative CRP
排除标准
- •Hepatitis B or C virus infection
- •HIV positive test
- •Chronic kidney disease
- •Thalassemia major patients with irreversible cirrhosis including 1-hyperglycemia 2-hyperalbuminemia 3-coagulopathy (INR> 1.5 and platelets <15000)
- •Symptoms of increased portal vein pressure include ascites, esophageal varices, splenomegaly
- •Research units have not tendency to continue the study
研究者
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