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临床试验/NCT06089174
NCT06089174已完成不适用

Assessment of the Increased Risk of Infection Following an Ultratrail

Centre Hospitalier Universitaire de la Réunion1 个研究点 分布在 1 个国家目标入组 471 人开始时间: 2023年10月6日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
471
试验地点
1
主要终点
Increased risk of infection

研究概览

简要总结

The increase in the practice of running has encouraged a proliferation of studies evaluating the impact of this sport on health. A number of these studies have looked at the influence of endurance events on the immune system. After prolonged exercise, a systemic inflammatory syndrome sets in, with repercussions for the functioning of the immune system. The number of lymphocytes in the blood is reduced, the function of natural killer (NK) cells is impaired and secretory immunity is impaired. During this period of immunosuppression, often referred to as the 'open window', the host may be more susceptible to micro-organisms that bypass the first line of defence.

The invetigators' hypothesis is therefore that ultratrailers are overexposed to the risk of infection due to immunodepression resulting from practising this sport. In order to support this hypothesis, the investigators would like to look at infectious complications in general and ear-nose and throat episodes (rhinitis, pharyngitis, laryngitis, etc.) in particular, which are the most common infections encountered in primary care, along with urinary tract infections.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • > 18 years
  • Participating in a Grand Raid de la Réunion 2023 race (Mascareignes, Trail de Bourbon, Diagonale des Fous)
  • Have a companion living under the same roof during the week preceding the race and the 21 days following the race and who agrees to answer the questionnaires
  • Do not object to the research

排除标准

  • Do not understand French
  • A protected adult (guardianship or curatorship) or under court protection

研究组 & 干预措施

Exposed (Runners)

Experimental

Ultra-endurance runners taking part in an ultra-trail of 72 km, 109 km or 165 km

干预措施: Ultra-trail (Other)

Non-exposed (companions)

No Intervention

Runners' companions not running

结局指标

主要结局

Increased risk of infection

时间窗: Day 21

Comparing the incidence of all infectious symptoms in runners taking part in one of the Grand Raid races (exposed subjects) with the incidence of infectious symptoms in those accompanying them on the race. fever, congestion, stuffy nose, sneezing, shortness of breath, vomiting, diarrhea, headache, sore throat, general fatigue, burning and urinary symptoms, other infectious symptoms; associated with major infections (respiratory, skin, gastrointestinal, urinary, other)

次要结局

  • Kinetic of infections' appearance(Day 21)
  • Risk factors: age category(Day 21)
  • Risk factors: running distance(Day 21)
  • Risk factors: training volume(Day 21)
  • Risk factors: sex of the runner(Day 21)

研究者

发起方
Centre Hospitalier Universitaire de la Réunion
申办方类型
Other
责任方
Sponsor

研究点 (1)

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