Lifestyle Factors, Inflammation, and Cognition in Breast Cancer Survivors
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 68
- 试验地点
- 1
- 主要终点
- Cognition
研究概览
简要总结
The purpose of this study is to examine the relationship between nutrition, physical activity and brain function in breast cancer survivors.
详细描述
The current study will examine the potential relationships between physical activity, dietary intake, body composition and cognition in breast cancer cancer survivors and age-matched women without a previous cancer diagnosis. Additionally, we will measure blood inflammatory markers to explore the relationship between lifestyle factors and inflammation.
The study involves two, 1hr appointments at Texas State University. The first visit will include cognitive testing and body composition assessment. Participants will be given an activity monitor to wear for one week and a packet of questionnaires to complete at home. At the second visit, a fasted blood sample will be collected, and participants will complete a food frequency questionnaire.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 30 Years 至 70 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Breast cancer survivors must have completed primary treatment (chemotherapy, radiation therapy or both) within past 60 months
- •age-matched controls must have no previous cancer diagnosis
- •no history of stroke, heart attack or transient ischemic attack
- •not currently pregnant; can speak, read, and write English
- •can attend all testing sessions
- •not blind or legally blind; nonsmoker
- •no current use of computer-based brain training games (e.g. Lumosity ®, BrainHQ ®).
排除标准
- •< 30 or > 70 years of age
- •breast cancer survivor > 60 months from last treatment or currently undergoing primary treatment
- •breast cancer survivor never treated with chemotherapy and/or radiation
- •previous cancer diagnosis other than breast cancer
结局指标
主要结局
Cognition
时间窗: Baseline
A series of computer-based cognitive tasks will be administered via the NIH Toolbox Cognition Battery
次要结局
- Physical Activity(Baseline)
- Diet Quality(Baseline)
- Body Composition (objectively measured)(Baseline)
- Inflammatory Markers(Baseline)
研究者
Krystle Zuniga
Assistant Professor
Texas State University, San Marcos